arbrolab@arbropharma.com   |     +91 8588851888    |    Mon – Sat, 9AM – 5 PM 

arbrolab@arbropharma.com   |     +91 8588851888 

Analytical Laboratories - HPLC

High-Performance Liquid Chromatography (HPLC)

At Auriga Research, we leverage the advanced capabilities of X-Ray Diffraction Analysis (XRD) to investigate crystalline material structures, including atomic arrangement, crystallite size, and imperfections. XRD is a non-destructive, powerful analytical tool that provides in-depth insights into the crystallographic structure, chemical composition, and physical properties of materials, making it indispensable in chemical, pharmaceutical, food, nutraceutical, herbal, organic products, and oil research.

hplc

Why Choose HPLC?

Comprehensive Applications

Used across industries such as pharmaceuticals, food, pesticides, and environmental testing, supporting regulatory compliance.

Sensitive and Precise

The method detects compounds in complex matrices with high sensitivity, supporting stringent quality control requirements

Versatility:

HPLC separates and quantifies a range of analytes, including polar, semi-polar, and nonpolar molecules, making it ideal for diverse applications.

Key Services

HPLC Testing

Comprehensive HPLC Analysis

Our HPLC instruments deliver precise quantification of components, ensuring quality, safety, and compliance for complex sample matrices.
Key Offerings:
  • Assay of drug products and formulations
  • Impurity profiling for pharmaceuticals
  • Quantification of vitamins and aflatoxins
  • Pesticide residue testing in food and water

Applications of HPLC

HPLC Testing
Pharmaceutical Industry

HPLC is indispensable in pharmaceuticals for purity testing, impurity profiling, and stability studies.

  • Drug Assays: Measures active ingredients in formulations to ensure dosage accuracy.
  • Impurity Profiling: Detects and quantifies trace impurities, essential for quality control.
  • Stability Testing: Monitors degradation products to support product shelf-life assessment.

HPLC Testing
Food Industry

HPLC helps ensure food quality by detecting vitamins, aflatoxins, and pesticides.

  • Vitamin Quantification: Accurately measures vitamins for nutrition labeling and regulatory compliance.
  • Aflatoxin Analysis: Detects aflatoxins, ensuring food safety in grains and nuts.
  • Pesticide Residue Testing: Screens for pesticide levels in food, meeting regulatory standards.

HPLC Testing
Nutraceutical Industry

HPLC is critical in nutraceutical testing, verifying the purity and quantity of bioactive ingredients for accurate labeling and quality.

  • Active Ingredient Quantification: Confirms levels of key nutraceutical ingredients to support health claims.
  • Heavy Metal Detection: Screens for heavy metals to ensure safety and compliance in health supplements.

HPLC Testing
Environmental Testing

HPLC is used to detect pollutants in water and soil, providing data for environmental protection.

  • Water Quality Testing: Measures organic contaminants in water and wastewater samples.
  • Pesticide Formulation Analysis: Assesses environmental impact by analyzing pesticide runoff.
  • Wastewater Analysis: Verifies that treated water meets environmental discharge standards.

HPLC Testing
Biomolecular Analysis

HPLC supports the analysis of proteins, peptides, and other biomolecules in various fields.

  • Protein Characterization: Determines protein purity in biomedical and biopharmaceutical research.
  • Peptide Analysis: Identifies peptides for research and clinical applications.
  • Enzyme Activity Measurement: Quantifies enzyme concentrations in bioassays.

HPLC Testing
Cosmetic Quality Control

HPLC verifies ingredient purity in cosmetics, especially for natural products, ensuring formulations meet regulatory and safety standards.

  • Fragrance Analysis: Identifies and quantifies essential oils and fragrance compounds in cosmetic formulations.
  • Preservative Testing: Monitors levels of preservatives to maintain product stability and consumer safety.

HPLC Testing

 

HPLC Testing

Advanced Testing Facilities:

Auriga Research operates 26 HPLC instruments from Waters, Jasco, Perkin Elmer, and Agilent, equipped with advanced detectors for diverse applications.

  • High-Precision Instruments: Our lab features UV, refractive index (RI), photodiode array (PDA), fluorescence, and mass spectrometer detectors for comprehensive analysis.
  • Automated Sampling: Auto-samplers on all HPLCs enable continuous 24/7 operation, maximizing accuracy, precision, and turnaround time.

HPLC Testing

 

HPLC Testing

Recent Methodologies:

Auriga integrates advanced HPLC methodologies tailored to different analytes:

  • Gel Permeation Chromatography: Analyzes macromolecules with high sensitivity.
  • Reverse Phase Chromatography: Ideal for semi-polar compounds.
  • Ion Pairing and HILIC Chromatography: Used for highly polar molecules, expanding testing flexibility.

HPLC Testing

 

HPLC Testing

Accreditations and Approvals:

Auriga Research maintains accreditations from NABL, FSSAI, FDA, and BIS, ensuring the highest standards in HPLC analysis.

  • NABL Accreditation
  • BIS Approval
  • FDA Certification
  • ISO Standards Compliance

 

HPLC Analysis: Our Expertise

Pharmaceutical Analysis

 

  • Assay and Impurity Profiling: Ensures active ingredient potency and quality control.
  • Method Development and Validation: Customized protocols for accurate and reproducible testing.

Environmental & Food Safety

 

  • Pesticide and Aflatoxin Testing: Detects contaminants to meet regulatory standards.

Nutraceutical and Biomolecular Testing

  • Vitamin and Protein Quantification: Confirms label accuracy and biomolecular quality.

Frequently Asked Questions (FAQs)

Our team of experts interprets XRD data to answer important questions regarding material identification, crystal form, polymorph identification, and the degree of crystallinity of amorphous materials.

We use the Xcelerator XRD Detector, a state-of-the-art model that allows for thorough testing of pharmaceutical compounds and reduces the lower limit of detection significantly.

The sample quantity required depends on the type of analysis. Simple XRD diffractograms can be done with as little as 1 gm of powder sample.

Yes, our lab routinely conducts tests for asbestos in talcum powder following recommended pharmacopoeial, ISO, and BIS methods.

Yes, XRD is fully capable of conducting polymorph identification tests, essential for understanding the solubility, dissolution rate, bioavailability, and stability of materials.

XRD provides non-destructive testing, detailed structural information, and is highly effective for polymorph identification, crystallinity analysis, and excipient compatibility studies.

XRD helps monitor food additives, control texture and stability, and ensure quality by providing detailed information on polymorphism, crystallinity, and amorphism.

XRD supports bioavailability analysis, stability studies, and ensures that nutraceutical products are stable and effective throughout their shelf life.

XRD analyzes the crystalline components of herbal products, ensuring their efficacy, safety, and compliance with quality standards.

XRD verifies the purity and quality of organic products, ensuring they are free from synthetic additives or contaminants and meet stringent standards.

XRD determines the crystalline structure of fatty acids in oils, affecting their stability and nutritional value, and ensures oils meet industry standards for purity and quality.

For any inquiries, please reach out to us:
Call us: +91 – 85 888 51 888
or
E-mail us: arbrolab@arbropharma.com

We look forward to assisting you with your testing requirements.